Read Leyton and Vezina (2012). Like Piazza, claim to have integrated the incentive sensitization and opponent process theories of addiction. Explain how they achieve this in the paper. How is this approach similar and different from Piazza’s approach in his 2013 paper? What are the roles (there are several) of dopamine in mediating the different psychological processes described in this paper?
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In the Vezina et al (2002) paper, they describe 3 experiments aimed at looking at dopamine sensitization and amphetamine self-administration. What do each of these experiments show? Be sure to include 1) a brief description (1-2 sentences) of the methods, 2) what the main conclusion was for each experiment, and 3) which graphs support this conclusion (3 points each experiment). For 3), make sure to focus only on the graph that shows the major effect, not the ancillary figures. For example, panel D of Figure 2 is not really important for the conclusions, it just shows where the microdialysis probes are.
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