Genome-wide CRISPR-Cas9 Screening Reveals Ubiquitous T cell Cancer Targeting via the monomorphic MHC class I related protein MR1

Crowther, M.D., G. Dolton, M. Legut, M.E. Caillaud, A. Lloyd, M. Attaf, S. A. E. Galloway, C. Rius, C.P. Farrell, B. Szomolay, A. Ager, A.L. Parker, A. Fuller, M. Donia, J. McCluskey, J. Rossjohn, I. M. Svane, J. D. Phillips & A. K. Sewell . Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature Immunology 21,178–185 (2020)

Using this article, create a presentation (no more than 20 slides) to discuss this article. 
Major points to include:
1. Brief introduction of the topic and background information
2. Identification of the pathways involved
3. Identification of the hypothesis of the research paper
4. Major findings description (with figures from the text)
5. Pitfalls and limitations
6. Identification of the next experiment 
7. Conclusion

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